Native Mass Spectrometry: The Essential Tool for Unraveling Protein Structures
In the world of scientific research, understanding the structure and function of proteins is essential for deciphering the molecular basis of life. Native mass spectrometry (MS) has emerged as a revolutionary technique, providing researchers with an unprecedented ability to study proteins in their native state without denaturation. This analytical tool is transforming the way scientists approach protein structure elucidation, allowing for more accurate insights into protein interactions , complex assemblies , and conformational changes that are crucial to understanding biological systems and diseases. By preserving proteins in their natural forms, native MS has become an indispensable tool in the quest for new scientific discoveries. Understanding the Basics of Native Mass Spectrometry Unlike traditional mass spectrometry techniques, which often require the proteins to undergo chemical denaturation or fragmentation, native mass spectrometry analyzes proteins and protein compl...